Ghanaian champions Aduana Stars will face Libyan side Al Tahaddy in the CAF Champions League preliminary round qualifier.
The first leg will be played between the weekend of 9-11 February 2018 and the return leg the following week.
Benghazi-based side won the Libyan Premier League last season.
Aduana Stars are returning to the continent's flagship inter-clubs competition since 2011.
They suffered early elimination at the hands of Moroccan side WAC after losing 3-0 in Casablanca but managed a 1-0 home win.
El Tahaddy SC are coming back after 40 years with their last appearance in the CAF Champions League dating back to 1978.