Berekum Chelsea have been handed a tough MTN FA Cup round of 64 draw against Mighty Jets.
The defending league champions rallied to draw 1-1 with Jets at the Accra Sports Stadium on the opening match day of the season's league.
But Chelsea, last season's semi-finalists, have improved and are favourites to advance against a Mighty Jets side who lie in the relegation zone.
League leaders and last season's losing finalists Asante drew third-tier side Swallah FC at the Baba Yara Stadium.
Hearts of Oak travel to Kintampo Shark Arrows;
Premier League debutants Wassaman United and Bechem United will clash at the Essipong Stadium in the one-leg competition.
The matches are scheduled for the weekend of 21-23 January 2012.
Full draw:
Dunkwa Utd vrs Liberty Youth FC
King Faisal vrs Rainbow FC
Berekum Chelsea vs Mighty Jets
Sp Mirren vs Pokuase Utd
Deportivo vs Golden Boots
RTU vs Unity FC
Wassaman vsBechem United
Aduana Stars vs King Solomon
FY Juventus vs AshantiGold
Medeama vs Westlandes
Yagbon Stars vs Heart of Lions
Pure Joy vs Soccer Legends
Asante Kotoko vs Swallah Utd
K Dom FC/Unistar Academy vs Elmina Sharks
Eleven Wise vs Guan United/Dynamos Fc
Kintampo Sharp Arrows vs Hearts of Oak
Swedru All Blacks vs Liberty Professionals
Dormaa Kyenkyenkye vs Okwahu United
Yegola FC vs Universal Stars
Danbort FC vs Tamale Utrecht
Kfc Samosa vs Fcm Maamobi
Berekum Arsenal vs Kessben FC
Bazooka FC vs Tarkwa United
Samartex FC vs Amidaus Professionals
New Edubiase vs B. A. United
Inter Allies vs Berlin FC
Dwarfs vs Believers FC
Hasaacas vs Bolga All Stars
Upper East United vs Wa All Stars
Kotoku Royals vs B.A Stars/Bongo United
Tema Youth vs Portmouth FC
Golden Eyes vs Great Olympics