Asante Kotoko slumped to their seventh defeat of the season with a 1-0 loss to in-form Inter AlliesÂ on Saturday.
The champions had to play their official home match at the Accra Sports Stadium due to a temporal ban.
Kotoko failed to pull 13 points clear at the top of the table after being undone by a late strike by Abdul Fatawu Safiu with a well-taken free kick.
The win sees the in-form Inter Allies climb up to 8th in the Ghanaian top flight - four points adrift the relegation zone.
Kotoko will maintain their position at the summit of the league with the remaining Week 26 fixtures to be playedÂ on Sunday.