England-based midfielder Emmanuel Frimpong has been handed his first call-up by Ghana for their 2014 World Cup qualifier against Sudan this month.
The Arsenal player, who is on loan at Fulham, is among four debutants named by Ghana coach Kwesi Appiah for the 24 March in Kumasi.
Left-back Baba Rahman of German Bundesliga club Greuther Furth, Sweden-based David Accam and Hearts of Oak attacker Mahatma Otoo are among the players called-up to the squad for the first time.
AC Milan star midfielder Sulley Muntari returns to the squad after missing the 2013 Africa Cup of Nations in January because of injury.
Also returning to the Black Stars are reigning Sweden league best player Abdul Majeed Waris, who recently signed for Russian giants Spartak Moscow and DR Congo-based defender Yaw Frimpong.
Fulham midfielder Frimpong comes into the Ghana national team for the first time after switching nationality last year to play for the country of his parents.
He comes as a massive boost for coach Appiah as midfielders Anthony Annan and Derek Boateng were left out of the team.
Left-back Baba Rahman, who is a big revelation in the German Bundesliga this season, comes into the squad for the first time in the attempt to Ghana's problems in that position.
Accam a pacy and skilful player has earned his call up following impressive displays for Helsingborg with Otoo expected to replicate his form at local giants Hearts of Oak.
The rest of the squad includes players who featured at the recent Africa Cup of nations with star performer Mubarak Wakaso, Rabiu Mohammed, Albert Adomah and Solomon Asante still part of the team.
Other top players like Agyemang Badu of Udinese, Juventus star Kwadwo Asamoah Christian Atsu and Asamoah Gyan will remain part of the solid squad while central defenders Isaac Vorsah and John Boye are also maintained.
Goalkeepers: Adam Kwarasey (Stromsgodset, Norway), Fatau Dauda (AshantiGold), Daniel Agyei (Liberty Professionals).
Defenders: Harrison Afful (Esperance, Tunisia), Yaw Frimpong (TP Mazembe, DR Congo), Richard Kissi Boateng (TP Mazembe, DR Congo), Baba Abdul Rahman (Greuther Furth, Germany), John Boye (Rennes, France), Jonathan Mensah (Evian, France), Isaac Vorsah (Red Bull Salzburg, Austria), Awal Mohammed (Maritzburg United, South Africa).
Midfielders: Emmanuel Frimpong (Fulham, England), Rabiu Mohammed (Evian, France), Emmanuel Agyemang Badu (Udinese, Italy), Kwadwo Asamoah (Juventus, Italy), Sulley Muntari (AC Milan, Italy), Christian Atsu (FC Porto, Portugal), Wakaso Mubarak (Espanyol, Spain), Solomon Asante (TP Mazembe, DR Congo), Albert Adomah (Bristol City, England).
Strikers:Â Asamoah Gyan (Al Ain, UAE), Abdul Majeed Waris (Spartak Moscow, Russia), David Accam (Helsingborg, Sweden ), Mahatma Otoo (Hearts of Oak).
What do you think of Ghana's squad to face Sudan? Are you satisfied with the players called up by Kwesi Appiah? Do you think any other players should have been invited or anyone dropped from the squad? Make your views known in the box below: