Medeama played out a 0-0 draw with Karela United at the Ndoum Stadium in Elmina to finish as Group B winners.
The Mauve and Yellows produced a better second half performance but could not find the back of the net thanks to some brave goalkeeping from Michael Sai for Karela.
Striker Kwame Boateng delivered a fabulous strike but the former Ghana U20 goalkeeper was up to task with a superb save.
This was in the 73rd minute and two minutes later right back Amos Korankye smashed in a belter but Sai again proved a barrier.
Medeama finished on top with seven points and followed by Hearts of Oak who beat Dwarfs 3-2 to amass six points.