Black Stars will have regular players start against DR Congo on Sunday in the quarter-final match in Oyem.
Head coach Avram Grant rested key players Thomas Partey, Frank Acheampong, Jordan Ayew and Mubarak Wakaso for the Egypt match on Wednesday which they lost 1-0.
But those players will be re-instated in the starting line up against the Congolese who topped Group D with wins against Togo and Morocco and a draw with defending champions Ivory Coast.
Ghana are seeking sixth consecutive Africa Cup of Nations semi-final berth.