Ashanti Gold SC are taking on newcomers Eleven Wonders FC at the Len Clay stadium on Wednesday as they aim at maintaining their momentum at the summit.
They go into the game with a setback in last weekend's fixture.
Medeama SC handed them their second loss of the season by beating them 2-1 with a penalty at the death.
The Elephants could make it nine straight wins at home if they see off the premier league debutants in the midweek.
The season's top scorer Shafiu Mumuni is out of Wednesday's game due to suspension.
He was sent off in Saturday's 2-1 defeat to the Mauves and Yellow in Tarkwa.
Stalwart defender Samed Ibrahim have not recovered fully from an injury he picked against Inter Allies FC about two weeks ago.
A slump in Wednesday's game could see the Gold and Black lads out of the top spot. They are levelled on points with Dreams FC.
Eleven Wonders FC are still seeking for their first away victory of the season with their visit to Obuasi to tackle the league leaders Ashanti Gold SC.
They have managed to pick only one point on the road after five travels.
The premier league new boys are going into the game with a defeat in their last fixture.
They were beaten 1-0 by Elmina Sharks FC at the Nduom Sports Complex last Sunday.
Newly signing Abdul Fatawu Safiu will need some time before making his debut for the Techiman based side. He joined them last week.
Striker Salifu Cisse remains on the sidelines with an injury. He could be returning back to the field in two to three weeks time.
Head To Head
Total league meetings = 0
Ashanti Gold SC wins = 0
Drawn matches = 0
Eleven Wonders FC wins = 0
• Ashanti Gold SC have lost just twice of their last ten fixtures in the premier league.
(W6 D2 L2)
• Eleven Wonders FC have recorded only two victories in their last seven matches in the premier league.
(W2 D0 L5)
• Ashanti Gold SC are unbeaten in their last eight home league games. All of them have been victories.
(W8 D0 L0)
• Eleven Wonders FC have been able to pick only one point from their five away games in the premiership this term.
(W0 D1 L4)
• This is the first and only time in the history of the premier league Ashanti Gold SC are hosting Eleven Wonders FC.
• Eleven Wonders FC have visited the Ashanti region once this campaign. They suffered a 1-0 loss to Asante Kotoko SC.
• Ashanti Gold SC have not conceded in any of their four home games in the premiership this season.
• Eleven Wonders FC have conceded in all of their five away fixtures in the premier league this campaign.
By Nuhu Adams