Ghana Premier League leaders Medeama drew Wa All Stars for the round of 32 fixtures of the MTN Ghana FA Cup.
The fixture is the only all-premiership pairing in this year's competition.
Hearts of Oak will face second-tier side BA Stars at home; Berekum Chelsea entertain Gomoa Fetteh Feyenoord and King Faisal play Mighty Jets in a mouth-watering contest.
In other interesting pairings, holder New Edubiase will face either Yassin FC or Starke FCÃ whose round of 64 match will be played next month.
Asante Kotok will also play third-tier side Agbozome Weavers in their outstanding round 64 tie.
Round 32 fixtures:
Heart of Lions vs. Samatex
Nania FC vs. Woe FC/Dawhenya FC
Yashin Stars vs. Starke/New Edubiase
King Faisal vs. Mighty Jets
XI Wise vs. Zaytuna
Prestige vs. Amidaus
Berekum Chelsea vs. Feyenoord
Hearts of Oak vs. BA Stars
Agbozome weavers vs. Kotoko/Japekrom
Great Olympics vs. Rainbow FC
FC Twente vs. GoldStars
Guan United vs. Hasaccas
Wa All Stars vs Medeama
Tema Youth vs Dynamo FC
Elmina Sharks vs AshantiGold
Aduana Stars vs All Blacks