The ten-time champions of the cup competition will welcome the GN Division One side to the Accra Sports Stadium as they bid to lift the coveted trophy that has eluded them for so long.
Asante Kotoko, meanwhile, will host another second-tier side Nea Salamina at the Baba Yara Sports Stadium while Ghana Premier League defending champions Wa All Stars will welcome fellow premier league side Berekum Chelsea to the Malik Jabir Park.
The matches are expected to played from the 29-30th July, 2017.
Below is the full draw:
Hearts of Oak vs Danbort
Medeama vs Amidaus Professionals
Asante Kotoko vs NEA Salamina
Wa All Stars vs Berekum Chelsea
Home teams of the quarter finals are expected to pocket GH₵4000 as preparatory bonus whilst away teams will pocket GH₵5000.