Michael Essien was assigned in a holding midfield role and lasted 74 minutes for Chelsea in their nervy 2-1 win over Wigan at the Stamford Bridge.
Nigeri international John Obi Mikel replaced him
In the Npower Championship, Prince Buaben played the last 18 minutes for Watford who lost 2-0 on home grounds to Blackpool.
Young striker Akwasi Asante was left out of the Birmingham City first team that thumped Crystal Palace 3-1.
Jeffrey Schulpp was introduced on the 81st minute mark for Leicester City as they cruised to a 4-0 win over Doncaster Rovers.
Albert Adomah came off the bench in the 54th minute to help Bristol City beat relegation rivals Nottingham Forest 1-0.
In the League One, Patrick Agyemang was brought on after the first 45 minutes but could not help Stevenage avoid a 3-0 defeat at the hands of Tranmere Rovers.
Former Liverpool striker David Amoo was excluded from the Bury team that lost 3-0 at Brentford.
Dutch-born Ghanaian striker Jonathan Opoku scored his seventh goal of the season by opening the scoring for Veendam in their 1-1 draw with Cambuur on Friday in the Dutch second-tier league.
Former Ajax Amsterdam youth team player Mitch Apau was replaced by Brazilian Vicente after 79 minutes for Veendam.
Former Ghana Under-17 striker Kelvin Bossman sat on the Helmond Sport bench as they recorded their seventh successive win with a 1-0 win over Volendam.
Ex Ghana international Eric Addo was axed from the 18-man squad of leaders FC Eindhoven who humbled Den Bosch 2-0.
Andre Ayew scored a 60th minute consolation goal for Olympique Marseille in their 2-1 loss to PSG on Sunday evening.
Young attacker Jordan Ayew came off the bench on the 90th minute mark for Marseille.
Jerry Vandam played a crucial role for Caen who pipped Bordeaux 1-0.
Bernard Yao Kumordzi lasted 82 minutes for Dijon who lost 2-0 to Nancy on home ground.
Defender John Boye was at the thick of affairs for Stade Rennes who hammered Evian Thonon Gaillard 3-1 away.
Boye wore a face mask to protect his nose injury.
Midfielder Rabiu Mohammed returned from injury to sit on the bench for Evian but defender Jonathan Mensah did not play for Evian.
Ghana captain John Mensah watched from the stands as his Olympique Lyon beat Auxerre 2-1 at the Stade de Gerland.
AS Monaco continued their surge in the Ligue 2 by booking their third consecutive win over the weekend as they edged Nantes 2-1.
Young defender Dennis Appiah lost his place in the Monaco first team.
Moussa Narry played one minute for Le Mans who beat Lens 3-1 at the Stade Félix Bollaert.
Winger Haminu Dramani lasted 67 minutes for Arles Avignon who were held to their third successive draw by Tours in a 2-2 draw.
In the reserves league, Kamal Issah played the full 90 minutes for Stade Rennes who drew 2-2 with Surze.
Kwame Nsor set up all two goals for Metz in their 2-1 win over Raon Etape.
Defender Daniel Opare was axed from the Standard Liege team who were held to a 0-0 draw by Anderlecht at the Stade Maurice Dufrasne in the championships play-offs.
Midfielder Dennis Odoi replaced Jordan Lukaku after 88 minutes.
Accra-born winger Gideon Boateng featured the entire period for CS Vise who drew 2-2 with leaders Sporting Charleroi in the Belgian second-tier.
Kwadwo Asamoah grabbed a double for Udinese as they beat Parma 3-1 at the Stadio Friuli on Saturday.
Asamoah scored in added time of either halves to help Les Zebrettes cruise to victory.
AC Milan surrendered their lead of the Serie A to Juventus after losing 2-1 at the San Siro to Fiorentina.
On loan Inter Milan midfielder Sulley Muntari lasted the entire duration of the game for Milan.
Kevin-Prince Boateng was not named in the Milan first team squad.
Young midfielder Amidu Salifu watched the entire action from the bench while striker Maxwell Acosty was nursing a thigh injury.
Afriyie Acquah reclaimed his starting place and lasted 62 minutes for Palermo who were beaten 2-0 by Juventus at their own backyard.
In the Serie B, Yaw Asante was an unused sub for Grosseto who held Bari to a 1-1 draw away.
Ahmed Barusso was brought on after the hour mark for Nocerina who beat Empoli 2-1.
Sassuolo remained in second spot despite failing to beat Modena at home in a 0-0 draw.
Striker Richmond Boakye-Yiadom was replaced after 55 minutes but compatriot Isaac Cofie played 90 minutes for Sassuolo.
In the Primavera league, Joseph Alfred Duncan played the entire match for Inter Milan to help them beat Vicenza 1-0.
Daniel Kofi Agyei captained Fiorentina to draw 1-1 with Sampdoria on Saturday. Defender Nii Nortey Ashong also played full time for Fiorentina.
Young goal machine Justice Opoku scored his 12th goal and won the king title as Inter Milan lost 1-0 to Senegalese club in the final of the World U-14 club championship in Spain.
Defender Isaac Vorsah played just 45 minutes for TSG Hoffenheim who defeated Kaiserslautern 2-1 at their own backyard.
Ghana-pursuit Karim Bellarabi played the last six minutes for Bayer Leverkusen in their 1-1 draw with Hamburg SV.
In the Bundesliga II, Charles Takyi was excluded from the St. Pauli team that drew 3-3 with FSV Frankfurt.
In the Bundesliga III, defender Marcel Appiah was at the heart of defence for Arminia Bielefeld who lost 5-0 at Unterhaching.
Dennis Danso Weidlich scored a 63rd minute consolation goal for Rot-Weiß Erfurt who lost 3-2 Preußen Münster.
Phil Ofosu-Aryeh played full time Rot-Weiß Erfurt.
Jeff Gyasi played the entire minutes for Rot-Weiß Oberhausen in their nil-nil Aalen.
Villarreal axed Wakaso Mubarak from the first team in their 3-1 loss at Real Betis.
Ghanaian starlet Paul Quaye was sent off for a rough challenge as Espanyol's reserves lost 3-2 at Clot.
There was no Prince Tagoe in the Bursaspor team that lost 2-0 on home soil against Gaziantepspor.
Youngster Torric Jibril failed to make the first team grade at Trabzonspor who drew 0-0 at Orduspor.
Jerry Akaminko was booked in the 51st minute and lasted the entire duration for Manisaspor who succumbed to a 4-0 defeat by Galatasaray.
Abdul Majeed Waris grabbed a double for Hacken who demolished Malmo FF 5-0.
Gefle IK drew 1-1 with Syrianska FC at their own backyard. Zakaria Abdullai came off the bench to play 11 minutes for Gefle.
Joachim Adukor was failed to make the first team grade for Gefle.
Former Asante Kotoko midfielder Yusif Alhassan Chibsah played the entire match for Djurgarden to beat GIF Sundsvall 1-0.
Joseph Baffo came off the bench as a 81st minute substitute for champions Helsingborg who beat Elfsborg 2-1.
In the second-tier league, Degerfors opened their campaign with a 3-1 home defeat to Jonkopings Sodra.
AIK Solna loanee Kwame Amponsah-Karikari lasted 79 minutes for Degerfors while former Ghana U20 defender Kassenu Ghandy played full throttle for Degerfors.
Mohammed Abubakar played the entire game for Doxa Dramas who were held to a 1-1 draw by Ergotelis.
Abdul Osman was in fine shape for Kerkyra who shocked giants Olympiakos 1-0 with ten men.
FC Porto loanee David Addy did not travel with Panaitolikos as they lost 1-0 at OFI Crete.
Winger Quincy Owusu-Abeyie was the starman for Panathinaikos as they cruised to a 3-0 win over Panionios.
Both Abeiku Quansah and Dominic Adiyiah were handed starting berths in Arsenal Kiev's 4-1 hammering of Obolon on Friday.
Quansah was substituted on the 50th minute mark while Adiyiah came out on the hour mark.
Former Ghana U20 defender Daniel Addo was introducedin the 64th minute for FC Zorya and he helped them to beat Chornomorets 3-2.
Khalif Alhassan came off the bench to play 28 minutes for Portland Timbers in their 2-1 home defeat by Chivas.
Charles Sapong played 88 minutes for Sporting KC in their slim 1-0 win over LA Galaxy.
Gershon Cofie lasted the entire match for Vancouver Whitecaps who lost 3-1 at San Jose Earthquakes.
Winger Quincy Osei was not involved in action for Hajduk Kula who held Radnici 1923 to a 0-0 draw.
Former Ghana captain Stephen Appiah did not feature for Vojvodina who lost 2-0 at home to Rad Beograde.
Former Asante Kotoko Nathaniel Asamoah made his Serbian league debut by coming on as a 65th minute substitute for Red Star Belgrade in their 5-0 home win over Metalac GM.
Kontoh Owusu-Ansah played the full 90 minutes for Metalac.
FC Midtjylland and Nordsjaelland played out a pulsating one-all drawn game at the MCH Arena.
Enock Adu-Kofi played 90 minutes for Midtjylland and Nordsjaelland respectively.
Christian Atsu Twasam set up the first goal for Rio Ave who drew 2-2 with Feirense.
In the second-tier, Alhassan Wakaso watched from the bench as his Portimonense drew 1-1 at Desportivo Aves with ten men.