Wa All Stars will play Ivorian champions AS Tanda on Friday afternoon at the WAFU Zone B tournament.
The Ghanaian champions trained on Thursday ahead of the start of the four-team tournament.
The other fixture will involve US Goree from Senegal, the hosts, and Liberian side Barracks Young Controllers.
Wa All Stars are seeking to make a huge impact after suffering early elimination from the CAF Champions League.