A new-look Karela United side will begin their campaign with a home-away-from-home clash against a plucky WAFA SC side at the Akoon Community Park in Tarkwa on Sunday.
The Nzema-Aiyinase side have their Cosby Awuah Memorial Park undergoing renovation works to meet the league's requirement and would have to co-share the pitch with Medeama.
On the pitch, a lot has changed in the last six months with head coach Johnson Smith leaving to join Asante Kotoko.
The club have lost regulars Jean Ourega Vital, Emmanuel Ocran, Maxwell Baakoh, Amos Kofi Nkrumah, Ampem Dacosta, Donald Wellington, Solomon Sarfo Taylor, Emmanuel Mintah, Isaac Kwain, Abdul Ganiu Ismail, Emmanuel Osei Baffour, Patrick Yeboah and Ibrahim Imoro.
One-time Premier League winning coach with Wa All Stars Enos Adepah has taken charge.
He can count on safest pair of hands Isaac Hagan, striker Diawisie Taylor, Franklin Osei, Alhaji Sani, Darlington Gyanfosu and Nurudeen Abdulai-who was superb during the Special Competition-for a solid performance.
WAFA SC's squad has not seen major changes with the old guards like Abukari Ibrahim, Aaron Justice Amate, Prosper Ahiabu and Daniel Lomotey all around to give them the needed experience.
Youngsters Kelvin Boakye-Yiadom, Martin Owusu will also get more game time to improve their stock.
Like their hosts, WAFA SC have employed new coach.
Prosper Narteh was installed just four days to the start of the season but that should not be a problem for the Sogakope side who have Sadiq Abubakar as deputy coach.
Karela United 2-1 WAFA SC