Two times Ghana Premier League champions Aduana Stars will welcome Dreams FC at the Nana Agyeman Badu II Park.
The hosts have had an inconsistent campaign and have won just a game in their last five matches and are eight on the table.
Meanwhile their opponents, Dreams have broken into the top four, after three wins in their last five games.
Dreams FC hammered Aduana in the first round in Dawu, with Joseph Esso, who left for Algeria, netting three times.
Aduana Stars are just four points adrift of top four wand will be hoping to return to form in earnest with just four games remaining.
The Ogya Boys are still without striker Yahaya Mohammed, but Bright Agyei and Benjamin Tweneboah are expected to play a crucial role.
Dreams FC will seek to consolidate top four spot with a positive result in Dormaa.
Prediction: Aduana Stars 2-1 Dreams FC