Asante Kotoko coach CK Akunnor has excluded experienced duo Jordan Opoku and Daniel Nii Adjei to face Coton Sport on Sunday in the CAF Confederation Cup playoff first leg tie.
They have been replaced by Stephen Nyarko and Prince Acquah as the Porcupine Warriors fly out on Friday to Yaounde.
Akunnor selected 18 players for the important clash and will be accompanied by seven technical officials, and a photojournalist.
The team left Kumasi on Thursday evening and will spend the night at an unnamed hotel in East Legon, Accra.
They will leave for the Kotoka International Airport early Friday morning.
Kotoko squad to face Coton Sport
Goalkeepers: Muntari Tagoe, Felix Annan
Defenders: Augustine Sefah, Ismail Abdul Ganiyu, Amos Frimpong, Abass Mohammed, Wahab Adams, Emmanuel Agyeman Badu.
Midfielders: Richard Senanu, Kwame Bonsu, Umar Basiru, Stephen Nyarko, Prince Acquah, Maxwell Baakoh, Emmanuel Gyamfi.
Strikers: Obed Owusu, Songne Yacouba, Safiu Fatawu