Ashantigold SC have left Obuasi for Accra ahead of their matchday two encounter against Hearts of Oak.
The Miners are traveling to Accra after drawing their opening day game against Karela United at the Obuasi Len Clay Park.
Meanwhile, hosts Hearts of Oak will be playing their first game of the season on Tuesday after their first game was postponed due to COVID-19.
The Phobians have now been cleared after a second test returned negative.
Last season when the two sides met in Accra, the game ended in a goalless draw.
Abednego Tetteh and Abdul Aziz Nurudeen who have recovered from COVID-19 remain out of Tuesday's encounter.
New signings Victor Aidoo and Nuru Sulley are in contention for their debuts as they are listed in the match squad.
Nigerien international Abdoulrahmane Mamane Lawali is also in the squad and could be making his debut for the Rainbow outfit when selected.
The Miners would need some motivation, confidence, and encouragement ahead of their CAF Confederation Cup game next week.
They play Burkina Faso side Salitas FC in the first leg of the preliminary round next Sunday.