The Black Stars team will leave Ghana for South Africa on Saturday ahead of Monday's second group G World Cup qualifier against the Bafana Bafana.
Ghana went top of the group after beating Ethiopia 1-0 in Cape Coast, and will immediately leave for early preparations ahead of the match against South Africa.
The team will be without England and Germany based players due to travel restrictions by the associations of both countries.
The English FA and the German football federation have banned players playing in their leagues from traveling to red zone areas, which includes South Africa.
This means Daniel Amartey, Andy Yiadom, Baba Abdul Rahman and Jordan Ayew will not travel to South Africa. Daniel Kofi-Kyereh, who made his debut on Friday and Braydon Manu will also not go to South Africa.
Coach C.K Akonnor might be forced into making some drastic last minute decisions including fielding some local players against the Bafana Bafana.
The Black Stars will be training at the FNB Stadium on Sunday before the game on Monday.