Berekum Arsenals beat newly crowned champions and cross-town rivals Chelsea 4-3 at Golden City Park to move from the drop; AshantiGold drew to go second.
Emmanuel Clottey maintained his hunt for the goal king crown by scoring the opener for Chelsea with a header before Stephen Amankwah equalized from the spot.
Amankwah grabbed a double by converting another penalty kick.
Striker Nana Poku also grabbed a brace to make it 4-1 but it was Clottey who stole the show by scoring a hat-trick.
Once again, Douglas Nkrumah was the saviour for Hearts of Oak as his first half goal sealed a 1-0 win over dethroned champions Aduana Stars in Accra.
King Faisal beat New Edubiase United 3-0 at the Baba Yara Stadium to pull from the relegation zone.
Micky Ofosu got off with the opener on four minutes; George Annan added the second and late in the game Abdul Wahab Yahaya gragged the third.
Real Tamale United thrashed 3-0 relegated BA Stars at the Tamale Stadium thanks to goals from Benjamin Boateng, a double, and Iddrisu Imoro.
AshantiGold moved to second place after earning a point from their goalless draw at home with All Stars.
Heart of Lions beat Ebusua Dwarfs 1-0 at the Kpando Park.
Earlier on Saturday, Mighty Jets beat Asante Kotoko 2-0 at the Ohene Djan Stadium.
Medeam Sporting Club dispatched Liberty Professionals 2-1 at the T&A Park in Tarkwa.Â