The four-time African champions take on the Bafana Bafana at the FNB Stadium in Johannesburg with a lot of stake for both nations.
Ghana, who need one win from their remaining two matches to qualify for next year's tournament, will battle the South Africans today before completing their qualification campaign against Sao Tome & Principe three days later in Accra.
And Ghanaian football club's welfare body, GHALCA, has sent a goodwill message to the national team.
— Ghana League Clubs Association (@GHALCA_) March 25, 2021
Sudan moved level with South Africa and Ghana, who face each other on Thursday afternoon, in the AFCON qualifying Group C standings after recording a comfortable 2-0 win over minnows Sao Time & Principe on Wednesday.