Ghana conceded an extra-time goal to lose 2-1 to Nigeria and failed to progress to final of the Wafu Nations Cup at the MKO Abiola Stadium in Abeokuta.
The match ended 1-1 in regulation time as the Siasia's troops nicked the winner in the 117th minute.
The Super Eagles could have sealed the game earlier in the first half of extra-time but wasted a spot-kick.
Nigeria will now play Togo in the final, who defeated Liberia in 4-2, in the first semi-final match.