Ludogorets Razgrad striker Bernard Tekpetey suffered an injury during his side's 2-0 defeat against CSKA 1948 in the 15th round of the Efbet League.
The 24-year-old was replaced after the hour mark after suffering the setback.
The Ghanaian striker is expected to undergo further test to determine the extent of injury.
Ivaylo Chochev opened the scoring for the side before Georgi Rusev added the second.
Ludogorets leads with 4 points ahead of the second-placed CSKA who have a game more to play.