Ghana thumped ten-man Namiba 7-0 in the Fifa Under-20 World Cup first qualifying round first leg tie at the Accra Sports Stadium.
US-based Florence Dadson grabbed a hat-trick and single strikes from captain Saahene, Elizabeth Addo, Faustina Ansah and Deborah Afriyie.
The Black Princesses travel to Windhoek for the reverse game on the weekend on 2-4 March, 2012.
The 2012 Fifa Under-20 World Cup will be held in Japan.