Ocansey Mandela scored his fourth CAF Champions League goal as Guinean side Horoya AC beat AS Togo-Port.
Compatriot and former WAFA SC teammate Brefo Mensah provided the assists for the goals.
Midfielder Farouk Mohammed converted a late penalty as Enyimba FC beat Djoliba in Mali.
GHANASoccernet.com's African football expert Nuhu Adams has a lowdown of how Ghanaian players fared in the CAF inter-clubs competitions.
CAF CHAMPIONS LEAGUE
Brefo Mensah was in his full elements as he assisted all two goals when Horoya AC beat AS Togo-Port 2-1 in Conakry on Friday.
Mensah could have gotten himself a goal eventually but he missed a spot kick.
Ocansey Mandela increased his tally in the competition to four after netting the first goal as the Guinean champions overcome AS Togo-Port.
Sebe Baffour Kyei lasted the entire duration to ensure Horoya AC claim all three points to put them second on the log.
Left back Hudu Yakubu impressed for AS Togo-Port despite their defeat to the Guineans.
He assisted the only goal for his side.
In eSwatini, Richard Sewu was an unused substitute as Mbabane Swallows suffered a 3-0 humiliation at the hands of Zambian giants ZESCO United.
CAF CONFEDERATION CUP
Enyimba FC edged closer to securing a spot in the quarter final after beating Djoliba AC at away on Sunday.
Former King Faisal and Elmina Sharks midfielder Farouk Mohammed got the solitary goal for the Nigerian champions through a spot-kick.
Tawrik Jebrin came on in the 92nd minute for Al Masry as they picked a point in Mozambique on Sunday.