Wolfsburg strikers Grafite and Edin Dzeko scored 54 goals together in Bundesliga 08/09 to help their team surprisingly won the league title. They were two points clear of second-placed Bayern. Messi and Eto'o are the second-best attacking duo in the top 5 leagues that season with 53 goals.
Top attacking duos in top 5 leagues 08/09:
Grafite & Dzeko - 54 goals
Eto'o & Messi - 53 goals
Forlan & Aguero - 49 goals
Higuain & Raul - 40 goals
David Villa & Juan Mata - 39 goals
Source: m.allfootballapp.com