Third-placed Aduana Stars host an improving Legon Cities side as they seek to close the gap on leaders Asante Kotoko.
The Fire Boys are on a six-match unbeaten run in all competitions and last lost a match on 06 February against Bibiani Gold Stars away.
In their last league match, coach Ben Zola and his boys managed a 1-1 draw at Real Tamale United.
At the weekend, they posted a 1-0 win over Berekum Chelsea to advance to the quarter-final of the MTN FA Cup.
After losing 1-0 to Bechem United at home in January, the former champions have collected the maximum points against Eleven Wonders, Karela and Hearts of Oak.
Legon Cities have been chequered but picking some important points which have seen them move to 12th on the table with 26 points.
Maxwell Konadu's side were punished on penalties last Sunday as they lost on penalties to Dreams FC at their adopted El Wak Sports Stadium home ground.