Medeama have been erratic but they are tipped for the points when they host King Faisal on Wednesday afternoon at the Akoon Park in Tarkwa.
The Mauve and Yellows were shocked at home in the last match to end the first round and that has been an opener.
They showed signs of recovery by beating Bechem United and Eleven Wonders in this early stages of the second half of the season.
In between that was a 1-0 defeat to Gold Stars in Bibiani.
Last week, they managed to earn a 1-1 draw at Karela United in a derby clash.
King Faisal have slipped to 10th on the league table after reverse results.
They have not won a match since beating WAFA on the road last month on the resumption of the second half of the league.
Faisal lost two consecutive matches- Aduana Stars at home and a 2-0 defeat at AshantiGold.
But at the weekend, they beat RTU 4-2 in Techiman and advanced to the quarter-final of the MTN FA Cup.