Liverpool had to settle for a 2-2 draw against Sevilla in Group E on their return to the Champions League.
Sevilla took the lead after just five minutes when Dejan Lovren got his feet mixed up and failed to cut out Sergio Escudero's pass across the six-yard box, and Wissam Ben Yedder was left completely unmarked to poke into the net.
Liverpool went looking for the equaliser straight away, and only had to wait until the 21st minute to find it. Alberto Moreno was the creator, cutting the ball back from the byline for Roberto Firmino to guide home with ease.
And the home side were almost in front two minutes later as Emre Can saw his angled drive go inches wide.
Joaquin Correa celebrates after levelling for Sevilla. Stu Forster/Getty Images
But Liverpool did take the lead in the 37th minute through Mohamed Salah, the Egypt international winning the ball off Steven N'Zonzi just outside the area before seeing his shot deflect off the heel of Simon Kjaer's boot and leave goalkeeper Sergio Rico helpless.
Liverpool were awarded a penalty just before half-time, Nicolas Pareja dragging down Sadio Mane inside the area. But Firmino couldn't make the most of it, as with Rico sent the wrong way he could only strike the ball against the post.
The second half had been short of incident, until Sevilla produced an equaliser in the 72nd minute. Luis Muriel fed Joaquin Correa on the edge of the box, who managed to take the ball in his stride and lift a shot past Loris Karius.
Jurgen Klopp immediately introduced Philippe Coutinho for his first appearance of the season after his summer transfer saga involving Barcelona, but the Brazil international could not inspire a winner.
To add to Liverpool's misery, Joe Gomez was sent off in stoppage time after receiving a second yellow card.