As expected, injured trio Eric Kwakwa, Rashid Nortey and Bright Enchil did not travel to the capital with the team.
Returnee Bernard Ofori also did not travel with the team after re-joining on a two-year deal.
However, coach Samuel Boadu has kept faith with the core of his team who have enjoyed a riveting start to the season so far.
Youngsters Nana Kofi Babil and Ebenezer Ackahabi keep their places in the team.
Medeama's travelling squad to face Liberty
Eric Ofori Antwi, Yaw Ansah, Samuel Appiah, Meshack Odoom, Philip Osei, Ali Ouattara, Daniel Egyin, Ibrahim Yaro, Richard Boadu, Michael Yeboah, Joseph Cudjoe, Agyei Boakye, Isaac Agyenim Boateng, Kwasi DAonsu, Prince Opoku-Agyemang, Nana Kofi Babil, Ebenezer Ackhabi, Joseph Tetteh Zutah.