Midfielder Mubarak Wakaso has undergone a successful surgery on his featured right hand.
The Ghana international suffered a fracture in the metacarpus of his right hand while in action for Alaves in their 4-2 defeat at the hands of Osasuna in La Liga on Sunday.
He is expected to make quick recovery after the international break. The 29-year old will miss Ghana's 2021 Africa Cup of Nations qualifiers this month.
The swashbuckling midfielder has been a mainstay in manager Asier Geratino's side this season, missing just a single game through suspension.
His absence will be a big blow for the El Glorisso, who lie 16th on the table, just two points off relegation.
The ex-Villareal man had a good nations cup in the summer, where was twice adjudged man of the match as the West Africans bowed out at the group stages.