Andre Ayew was denied the opportunity of playing alongside his brother at Wembley after the 19-year-old Jordan  was omitted from a 24-man Ghana squad for matches against Congo and England.
The brothers have played together at French club Olympique Marseille but there was no call-up for Jordan Ayew for the matches in Brazzaville on March 27 and Wembley two days later.
He provided an assist for Marseille in a key Ligue 1 match against Stade Rennes last Friday and had been expected to link up with his 22-year-old brother in an exciting double act.
With Michael Essien not tempted to return from his national team sabbatical to take on some of his Chelsea team mates Ghana's new coach Goran Stevanovic opted for a tried and tested combination with one new cap and one recall.
Daniel Opare of Standard Liege gets a recall and striker Nathaniel Asamoah from Asante Kotoko is called up for the first time.