Tom Barkhuizen pounced on a loose Wycombe header to score his fifth goal of the season after 14 minutes
An 87th minute own goal from Jason McCarthy earned Preston North End a point and denied Wycombe their first win in six games.
Tom Barkhuizen put Preston ahead at Deepdale after 14 minutes and they held the lead until early in the second half.
Garath McCleary equalised after 48 minutes and Scott Kashket put Wycombe ahead with fifteen minutes left.
But McCarthy made a mess of Scott Sinclair's cross and diverted the ball past Ryan Allsop to ensure the game ended in a draw.
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Wycombe had an early let-off when Sinclair's 20-yard effort curled inches wide inside 60 seconds.
But the reprieve didn't last long as in-form Lilywhites forward Barkhuizen scored his fourth goal in five games after pouncing on a mistake.
Josh Knight's header sold his goalkeeper short and the alert Barkhuizen reacted quicker than anyone else to nod it over Allsop for the opener.
Wycombe responded well and were making chances of their own, with Adebayo Akinfenwa going close with a header.
They went closer still when Knight saw an effort cleared off the line by Ben Davies and McCleary's follow-up went behind for a corner.
The Chairboys were back on level terms when Daryl Horgan spotted the run of McCleary and slid the ball through for the forward to fire emphatically into the roof of the net.
It got better still for Wycombe when Scott Kashket grabbed his fourth of the season, finishing well after Joe Jacobson's 25-yard free-kick came back off the post.
It looked like being enough to claim the three points before McCarthy turned the ball into his own goal under pressure from Jayden Stockley.
Wycombe Wanderers manager Gareth Ainsworth told BBC Three Counties Radio:
"I'm gutted but it's a positive to [be able to] say that after not getting three points away at Preston, even though we deserved it.
"Having said that, you can't concede two goals. The first one is really sloppy, the second one is very unlucky.
"I think we could have had a few more ourselves today, we had some real clear-cut chances but unfortunately we didn't stick them in. You've got to do that in the Championship.
"In the last two games we've been super competitive and I'm looking forward to what we can do at Barnsley."
- Line-upsMatch StatsLive Text
Line-upsPreston
- 1Rudd8Browne23Huntington6Davies15RaffertySubstituted forStockleyat 73'minutes18Ledson4PearsonSubstituted forHarropat 33'minutes29Barkhuizen11JohnsonSubstituted forPottsat 73'minutes31Sinclair24MaguireSubstituted forRiis Jakobsenat 61'minutes
Substitutes
- 7Bayliss10Harrop14Storey19Riis Jakobsen20Stockley25Ripley27Holland-Wilkinson32O'Reilly44Potts
Wycombe
- 1Allsop2GrimmerBooked at 83mins12KnightBooked at 26mins5StewartSubstituted forWheelerat 67'minutes3Jacobson26McCarthy17HorganSubstituted forFreemanat 79'minutes19McCleary11KashketBooked at 86mins20AkinfenwaSubstituted forSamuelat 84'minutes23OnyedinmaSubstituted forBloomfieldat 79'minutes
Substitutes
- 7Wheeler8Pattison10Bloomfield22Freeman25Samuel27Parker31Stockdale33Mehmeti34Burley
Referee:James LiningtonMatch StatsHome TeamPrestonAway TeamWycombePossessionHome60%Away40%ShotsHome19Away17Shots on TargetHome2Away4CornersHome8Away6FoulsHome17Away15Live TextPost update
Match ends, Preston North End 2, Wycombe Wanderers 2.
90'+8'Full Time
Second Half ends, Preston North End 2, Wycombe Wanderers 2.
90'+6'Post update
Attempt missed. Emil Riis Jakobsen (Preston North End) right footed shot from the centre of the box misses to the left following a corner.
90'+5'Post update
Corner, Preston North End. Conceded by Scott Kashket.
90'+4'Post update
Attempt missed. Alex Samuel (Wycombe Wanderers) header from the centre of the box misses to the right. Assisted by Garath McCleary with a cross.
90'+2'Post update
Attempt missed. Emil Riis Jakobsen (Preston North End) right footed shot from the right side of the box misses to the right. Assisted by Declan Rudd.
90'Post update
Attempt blocked. Ryan Ledson (Preston North End) right footed shot from outside the box is blocked. Assisted by Jayden Stockley.
88'Post update
Foul by Jayden Stockley (Preston North End).
88'Post update
Jack Grimmer (Wycombe Wanderers) wins a free kick in the defensive half.
87'goalGoal!
Own Goal by Jason McCarthy, Wycombe Wanderers. Preston North End 2, Wycombe Wanderers 2.
86'Booking
Scott Kashket (Wycombe Wanderers) is shown the yellow card for a bad foul.
86'Post update
Alan Browne (Preston North End) wins a free kick in the attacking half.
86'Post update
Foul by Scott Kashket (Wycombe Wanderers).
84'Post update
Attempt missed. Jayden Stockley (Preston North End) header from the centre of the box misses to the left. Assisted by Ryan Ledson following a set piece situation.
84'Substitution
Substitution, Wycombe Wanderers. Alex Samuel replaces Adebayo Akinfenwa.
83'Booking
Jack Grimmer (Wycombe Wanderers) is shown the yellow card for a bad foul.
83'Post update
Jayden Stockley (Preston North End) wins a free kick in the attacking half.
83'Post update
Foul by Jack Grimmer (Wycombe Wanderers).
82'Post update
Foul by Alan Browne (Preston North End).
82'Post update
Joe Jacobson (Wycombe Wanderers) wins a free kick in the defensive half.
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Source: bbc.com