Asante Kotoko say they will be without three key players for their regional derby against King Faisal on Saturday afternoon.
Right back Christopher Nettey, left back Patrick Asmah and centre-back Habib Mohammed have been ruled out.
The trio sustained their injuries in the 1-0 against Hearts of Oak in Accra last weekend.
The defeat to Hearts has left Kotoko needing a miracle to win the Ghana Premier League title.
With three games to go, Kotoko are three points behind Hearts who also have a better head to head, so the Phobians need six points to be crowned champions.
Meanwhile, Kotoko must win all their games and hope Hearts drop points.