Goalkeeper Richard Kingson will captain Ghana in the absence of John Mensah for Wednesdayâ€™s friendly against South Africa at the Soccer City Stadium.
The 32 year-old who kept the post for the Black Stars at the 2010 World Cup arrived in the teamâ€™s camp on Tuesday as Milovan Rajevac prepares his side for the first game since they went out in the quarter-final stages at the World Cup in South Africa.
Rajevac has replaced Mensah with Under-20 youngster Bright Addae.
The Sunderland defender is the second player to pull out after Dominic Adiyiah.
Kevin-Prince Boateng has also withdrawn from the squad leaving Rajevac with a 17-man squad.
Goalkeepers: Richard Kingson (Unattached), Daniel Agyei (Liberty Professionals, Ghana)
Defenders: Samuel Inkoom (Basel, Switzerland) Harrison Afful (Esperance, Tunisia) Bright Addae (Parma, Italy), Lee Addy (Bechem Chelsea, Ghana) Jonathan Mensah (Granada, Spain)
Midfielders: Anthony Annan (Rosenborg, Norway), Emmanuel Agyemang-Badu (Udinese, Italy), Kwadwo Asamoah (Udinese, Italy) Andre Ayew (Marseille, France) Kevin-Prince Boateng (Portsmouth, England) Cofie Bekoe (Petrojet, Egypt) Bernard Kumordzi (Panionios FC, Greece)
Attackers: Asamoah Gyan (Rennes, France), Ransford Osei (FC Twente, Holland) Haminu Draman (Locomotiv Moscow, Russia) Yaw Antwi (FK Vojvodina, Serbia)