Holders Ahly of Egypt produced another error-ridden display to suffer a 3-2 African Champions League loss at home to Ahly Benghazi that sent them packing on Saturday, denying them a chance to win an unprecedented third consecutive title.
The Cairo giants were eliminated with a 4-2 aggregate defeat, having slumped to a 1-0 first-leg defeat in Tunisia.
They still have a chance to add to their 19 continental titles, a world record, as they will feature in the African Confederation Cup, the continent's secondary club competition.
Saturday's defeat by Benghazi at Cairo's Air-Defence Stadium marked the first time Ahly bow out in the round of 16 since they lost to Nigeria's Kano Pillars at the same stage in 2009.
It is also their ninth loss in 18 matches in all competitions this season, a dismal record under coach Mohamed Youssef who reports suggest will be shown the door.